Tag: incurable
Base editing: Revolutionary therapy clears girl’s incurable cancer
Teenager’s Incurable Cancer Cleared With Revolutionary DNA-Editing Technique
Doctors at Great Ormond Street Hospital used “base editing” to perform a feat of biological engineering to build her a new living drug. Six months later the cancer is undetectable, but Alyssa is still being monitored in case it comes back.
Alyssa, who is 13 and from Leicester, was diagnosed with T-cell acute lymphoblastic leukaemia in May last year…. Her cancer was aggressive. Chemotherapy, and then a bone-marrow transplant, were unable to rid it from her body…. The team at Great Ormond Street used a technology called base editing, which was invented only six years ago [which] allows scientists to zoom to a precise part of the genetic code and then alter the molecular structure of just one base, converting it into another and changing the genetic instructions. The large team of doctors and scientists used this tool to engineer a new type of T-cell that was capable of hunting down and killing Alyssa’s cancerous T-cells….
After a month, Alyssa was in remission and was given a second bone-marrow transplant to regrow her immune system…. Alyssa is just the first of 10 people to be given the drug as part of a clinical trial.
Her mother said that a year ago she’d been dreading Christmas, “thinking this is our last with her”. But it wasn’t.
And the BBC adds that applying the technology to cancer “only scratches the surface of what base editing could achieve…. There are already trials of base editing under way in sickle-cell disease, as well as high cholesterol that runs in families and the blood disorder beta-thalassemia.”
Read more of this story at Slashdot.
Celine Dion Reveals She Has Incurable Disease, Postpones 2023 Shows to 2024
Celine Dion fans will have to wait a while longer for the superstar’s return to the stage.
Because continued health challenges have forced the diva to postpone a series of 2023 shows until 2024 while scrapping some concerts in their entirety.
Full story below…
As reported, Dion went public with news of the medical issues she has been experiencing when indefinitely postponing the start of her new Las Vegas residency.
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