Skyrim modders are to bring DLSS, FSR2, and XeSS upscaling to the Anniversary and Special Editions of the game.
Modder PureDark is working on the plugin alongside other modders. Called Skyrim-Upscaler, it is available through GitHub, and a public release will occur once the team works out VR compatibility (thanks, RPS).
The plugin looks to increase frame rates with other Skyrim mods installed, but at present, it won’t work with the popular ENB (Enhanced Natural Beauty) mod. That said, compatibility between ENB and DLSS is in the works.